161. Preliminary results of the study on botany and chemical composition of Schefflera sp3

Vo Duy Huan, Tran Cong Luan, Duong Hong To Quyen

During the screening of the genus Schefflera, an unidentified Schefflera species was found. This paper presents the results of the studies on botanical and anatomical characteristics of this plant. Preliminary studies on chemical composition of the leaf, stem and trunk were also done. Qulitative analysis of the chemical composition revealed that the leaf, stem and trunk contain saponins, phytosterols, reduced sugars, tannin, coumarins, organic acids and uronic compounds. The quantitative determination of fatty acids and trace elements were also made.

167- Polymorphism of black snake venom RNase. I- Two distinct kinetical forms

Nguyen Van Thiet

Ribonuclease of Vietnam black cobra (Naja naja) venom has been characterized by kinetical method. This enzyme proves to consist of two distinct forms in agreement with the kinetical model 2p ↔ P, where p is probably a monomer and P is a dimer. Thse forms considerably differ in specific activity. At pH 2.60, i.e., the pH value near the optimum, the monomer form is active whereas the dimer is not. At pH 7.32, however, the monomer is almost inactive while the dimer is active.

170- Monoamine oxidase inhibitory effect of Vietnamese plants

Nguyen Manh Cuong, Tran Van Sung, Nguyen Tien Dat, Young Ho Kim

Methanol extracts prepared from twenty eight Vietnamese plants were screened for the inhibitory activity in vitro against mouse brain monoamine oxidase (MAO). Three plant extracts showed more than 50% inhibition on MAO activity at a concentration of 400 μg/ml. These active extracts were fractionated in different solvents and tested to determine the MAO inhibitory fractions. Among them, the ethyl acetate and butanol fractions of the methanol extract from the leaves of Eurya ciliata Merr. (Theaceae) inhibited 74.7 and 87.2 % monoamine oxidase activity, respectively, at the concentration of 400 μg/ml.

173- Experimental induction of Prostatic Hypertrophy in rats for study of leaf extract of Crinum asiaticum L.

Do Trung Dam, Nguyen Ba Hoat, Le Minh Phuong, Nguyen Kim Phuong, Do Thi Phuong

Prostatic hypertrophy was successfully induced by testosterone in rats. The method is reliable and can be used in screening for drugs capable of inhibition of prostatic hypertrophy. This model has proved the leaf extract of Crinum asiaticum L., a medicinal plant in Vietnamese traditional medicine, to be effective against the hypertrophy of prostate in rats.

176- Studies on effects of Morinda citrifolia fruit extract on constitution and hematogenesis in rats

Nguyen Trong Thong, Pham Thi Van Anh, Vu Thi Ngoc Thanh

Semi-dried extract of Morinda citrifolia fruit (1ml contains 2g fresh fruit) was used to evaluate it's influence on general status, body weight and hematogenesis in experimental rabbits.

The results show that the extract in daily oral doses of 6 g/kg and 12 g/kg body weight (corresponding to 10 and 20 times of the clinical dose, respectively) in a 30-day course have not influenced the general status, the body weight and the blood forming fuction.

180- Evaluation of anti-inflammatory and analgesic effects of different formulations made from a massage tincture

Nguyen Thi Xuan Hoa, Pham Van Thanh, Pham Kim Man, Nguyen Thi Minh Khai

In order to improve efficacy, safety and convenience of a massage tincture, a traditional anti-inflammatory and analgesic prescription, various formulations have been made from it and their effects have been evaluated experimentally using the tincture and diclofenac gel 2%, a patent medicine of the kind, as reference preparations. The results show that fomulations of 5% propylene glycol and emulgel are more effective in anti-inflammation and analgesia than the tincture itself.

183- Effects of Macrotermes anadelei and Polyrachis dives on process of learning and memorization

Nguyen Thi Van Thai

Water extracts of Macrotermes anadelei and Polyrachis dives were shown to improve memorization power of experimental rats in one trial learning avoidance test, and mice in Morris Water Maze.

187- Identification of the plant material of polygonatums by microscopic investigation

Nguyen Viet Than, Nguyen Thi Chung

189- Chemical composition of Atalantia roxburghiana oil collected from Me Linh- Vinh Phuc

Lai Thi Van, Dao Van Phan, Nguyen Duy Thuan, Pham Minh Hung

191- Adenosma glutinosum (L.) Druce

Do Huy Bich