1. Title of technological and scientific service

Service of research and development of extraction technology of  materials from natural origin for drug production, technological process of  essential oil distillation, purification of  crude drugs. Service of extraction of many kinds of medicinal materials into products on request. Production and supply of  semi-finished and finished drug products, aromas and cosmetics. 

2. Brief description of service 

Medicinal material processing "Extraction"Solvent recovery under  decreased pressure" Elimination of impurities "Crude drugs"Purification"Desiccation under decreased pressure.

Equipment: Multi-purpose extraction plant, Film evaporation unit , Vacuum filtration unit centrifuger, Agitator, Reaction unit complete- Vacuum bath drying unit- Liquid – Liquid extraction unit. These French and German apparatus are used for extraction  in semi-industrial scale.

3. Possible users of service 

Pharmaceutical companies, cosmetic manufacturers, companies of production and processing of Foodstuffs, research institutes in and out of pharmaceutical branch.

4. Condition for service supply 

Agreement contract 

1. Title of technological and scientific service

Research service of extraction of active substances from medicinal plant materials  for dosage formulation 

2. Brief description of service 

Extraction of active substances from medicinal plant materials on request 

3. Possible users of service

Companies, manufacturers, individuals who have demand and conditions for drug production

4. Condition for service supply 

Agreement contract

1. Title of technological and scientific service 

Trial of drug effect on intestinal contraction 

2. Brief description of service 

Applying method of Magnus on isolated intestine of rabbit 

Isolated intestine is put in French Apelex isolated organ unit apparatus with isotonic transducer 7006. The change of the systaltic activity of intestine is recorded by Italian Gemini two – channel recorder 

3. Possible users of service 

+ Research Units of Medicinal materials and  drug effects 

+ Students, post-graduat students of pharmacy and medicine 

+ Drug manufacturers 

4. Condition for service supply 

Agreement contract 

1. Title of technological and scientific service 

Trial of cardiotonic effect 

2. Brief description of service 

Trial of inotropic , chronotropic effects and effect on coronary blood flow on Langendorff isolated heart of rabbit, that is put in French Apelex isolated organ apparatus with isotonic transducer. Through aorta the coronary arteries are perfused with oxygenated Ringer Locke solution 

3. Possible users of service 

+ Research Units of Medicinal materials and  drug effects 

+ Students, post-gradutate students, PhD of pharmacy and medicine 

+ Drug manufacturers 

4. Condition for service supply 

Agreement contract 

1. Title of technological and scientific service 

Trial of antipyretic action of drug 

2. Brief description of service 

Agent causing pyrexia is pyrogen. 

Measurement of  the body temperature of rabbits at different times by Digital temperature instrument for animals 

3. Possible users of service 

+ Research Units of Medicinal materials and  drug effect 

+ Students, post-graduate students of pharmacy and medicine 

+ Drug manufacturers 

4. Condition for service supply 

Agreement contract 

1. Title of technological and scientific service 

Trial of diuretic action of drug 

2. Brief description of service 

Trial of diuretic action of drug by measurement of urinary output and determination of content of urinary Na⁺, K ⁺ on semi-automatic biochemistry analyser 

3. Possible users of service 

+ Research Units of Medicinal materials and  drug effects 

+ Students, post-graduate students of pharmacy and medicine 

+ Drug manufacturers 

4. Condition for service supply 

Agreement contract 

1. Title of technological and scientific service 

Trial of vasolidator and increasing cerebral blood flow effects of drugs 

2. Brief description of service 

Celebral blood flow through carotids and other arteries is measured by American transonic animal 

research flowmeter T206 

3. Possible users of service 

 Research Units of Medicinal materials and  drug effects 

Students, post-graduate students of pharmacy and medicine 

Drug manufacturers 

4. Condition for service supply 

Agreement contract

1. Title of technological and scientific service 

Trial of antihypertensive effect of  drug 

2. Brief description of service 

Using bloody method for direct measurement of arterial blood pressure through carotid artery of anesthetized cat. The change of blood pressure of cat by drug is measured by electronic manometer 

3. Possible users of service 

+ Research Units of Medicinal materials and  drug effect 

+ Students, post-graduate students of pharmacy and medicine 

+ Drug manufacturers 

4. Condition for service supply  

Agreement contract 

1. Title of technological and scientific service 

Trial of anti-inflammatory effect of drugs 

2. Brief description of service 

- Acute antiinflammatory effect (Method of Winter et al.) : Rat paw oedema induced by carrageenan, is measured by Ugo-Basil plethysmometer-7140 

- Chronic antiinflammatory effect : Method of Ducrot, Julou et al., : Granuloma, induced by asbestos in rats, is weighed.

3. Possible users of service 

+ Research Units of Medicinal materials and  drug effects 

+ Students, post-graduate students of pharmacy and medicine 

+ Drug manufacturers 

4. Condition for service supply 

Agreement contract 

1. Title of technological and scientific service 

Trial of analgesic effect 

2. Brief description of service 

- Method of Koster et al.: Paiful writhing induced in mice by intraperitoneal injection of 1% acetic acid 

- Hot plate method of Eddy and Leimbach: Pain is induced in rats by thermal stimulus, using Ugo-Basil Heating plate analgesimeter 

3. Possible users of service 

+ Research Units of Medicinal materials and  drug effects 

+ Students, post-graduate students of pharmacy and medicine 

+ Drug manufacturers 

4. Condition for service supply 

Agreement contract 

1. Title of technological and scientific service 

Trial of hypocholesterolemic effect 

2. Brief description of service 

Method of Kellner Correll and Ladd : Induction of hypercholesterolemia by intravenous injection of tween 80. Determination of blood cholesterol levels before and after tween 80 injection by semi-automatic biochemistry analyser. 

3. Possible users of service 

+ Research Units of Medicinal materials and  drug effect 

+ Students, post-graduate students of pharmacy and medicine 

+ Drug manufacturers 

4. Condition for service supply 

Agreement contract

1. Title of technological and scientific service 

      Trial of antidiabetic effect of drugs 

2. Brief description of service 

- Experimental diabetes are induced by intravenous injection of alloxan monohydrate in mice 

- Determination of blood glucose of mice before and after alloxan injection by semi-automatic biochemistry analyzer

3. Possible users of service 

+ Research Units of Medicinal materials and  drug effects 

+ Students, post-graduate students of pharmacy and medicine 

+ Drug manufacturers 

4. Condition for service supply 

           Agreement contract